The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 2018
Filed:
Nov. 21, 2014
Applicant:
University of Kentucky Research Foundation, Lexington, KY (US);
Inventors:
David S. Watt, Lexington, KY (US);
Chunming Liu, Lexington, KY (US);
Vivek Rangnekar, Nicholasville, KY (US);
Vitaliy M. Sviripa, Lexington, KY (US);
Ravshan Burikhanov, Lexington, KY (US);
Wen Zhang, Lexington, KY (US);
Assignee:
University of Kentucky Research Foundation, Lexington, KY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 215/38 (2006.01); C07D 215/06 (2006.01); A61K 31/47 (2006.01); C07D 495/04 (2006.01); C07D 215/227 (2006.01); C07D 215/36 (2006.01);
U.S. Cl.
CPC ...
C07D 215/38 (2013.01); A61K 31/47 (2013.01); C07D 215/06 (2013.01); C07D 215/227 (2013.01); C07D 215/36 (2013.01); C07D 495/04 (2013.01);
Abstract
The subject technology relates to arylquinoline compounds and their use for treating cancer or cancer metastasis. The compounds of the subject technology promote cells to secrete a pro-apoptotic tumor suppressor, i.e., prostate apoptosis response-4 (Par-4), which in turn promote apoptosis in cancer cells or metastatic cells.