The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 2018
Filed:
Oct. 17, 2013
Daiichi Sankyo Company, Limited, Tokyo, JP;
Hiroyuki Naito, Tokyo, JP;
Takashi Nakada, Tokyo, JP;
Masao Yoshida, Tokyo, JP;
Shinji Ashida, Tokyo, JP;
Takeshi Masuda, Tokyo, JP;
Hideki Miyazaki, Tokyo, JP;
Yuji Kasuya, Tokyo, JP;
Yuki Abe, Tokyo, JP;
Yusuke Ogitani, Tokyo, JP;
DAIICHI SANKYO COMPANY, LIMITED, Tokyo, JP;
Abstract
As an antitumor drug which is excellent in terms of antitumor effect and safety, there is provided an antibody-drug conjugate in which an antitumor compound represented by the following formula (I) is conjugated to an antibody via a linker having a structure represented by the following formula: -L-L-L-NH—(CH)n-L-L-L- or -L-L-L- wherein the antibody is connected to the terminal of L, the antitumor compound is connected to the terminal of Lor L, and any one or two or more of linkers of L, L, and Lhas a hydrophilic structure.