The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 2018
Filed:
Dec. 01, 2010
Applicants:
Ulrich Von Andrian, Chestnut Hill, MA (US);
Silke Paust, Jamaica Plain, MA (US);
Inventors:
Ulrich Von Andrian, Chestnut Hill, MA (US);
Silke Paust, Jamaica Plain, MA (US);
Assignee:
President and Fellows of Harvard College, Cambridge, MA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); C07K 16/28 (2006.01); A61K 38/19 (2006.01); C12Q 1/02 (2006.01); A61K 38/17 (2006.01);
U.S. Cl.
CPC ...
A61K 45/06 (2013.01); A61K 38/177 (2013.01); A61K 38/195 (2013.01); A61K 39/3955 (2013.01); C07K 16/2866 (2013.01); C12Q 1/025 (2013.01); A61K 2039/505 (2013.01);
Abstract
The instant invention is based, at least in part, on the discovery that CXCR6 plays a critical role in antigen-specific effector function of NK cells. Accordingly, the invention provides, among other things, methods for modulation of antigen-specific NK cell effector function, methods for identifying modulators of antigen-specific NK cell effector function.