The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 23, 2018

Filed:

Apr. 04, 2017
Applicant:

New Phase Ltd., Givat Shmuel, IL;

Inventors:

Raphael Hof, Kfar-Yona, IL;

Raz Khandadash, Bat-Yam, IL;

Ella Fremder, Haifa, IL;

Assignee:

NEW PHASE LTD., Givat Shmuel, IL;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 41/00 (2006.01); A61N 1/40 (2006.01); A61K 47/48 (2006.01); A61K 47/06 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0052 (2013.01); A61K 47/06 (2013.01); A61K 47/48215 (2013.01); A61K 47/48907 (2013.01); A61N 1/406 (2013.01);
Abstract

Apparatus and methods are described for use with a subject suffering from cancer. A nanoparticle () includes an inner core () that comprises a phase-change material that is configured to absorb latent heat of fusion by undergoing a phase change. An outer layer () disposed around the inner core includes a plurality of nano-spheres () of at least one metal, and a plurality of molecules () of a substance that binds preferentially with cancerous cells relative to non-cancerous cells. The nanoparticle has a volume of at least 65,000 nmand is elongatable into an ellipsoid, such that, when the nanoparticle is maximally elongated, each of the semi-axes defined by the ellipsoid is greater than 5 nm, and at least two of the semi axes of the ellipsoid are less than 30 nm. Other applications are also described.


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