The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 2018
Filed:
Mar. 29, 2012
Dhiraj Khattar, Gurgaon, IN;
Rajesh Khanna, Gurgaon, IN;
Sanjay Motwani, Gurgaon, IN;
Minakshi Garg, Gurgaon, IN;
Vikas Chandel, Gurgaon, IN;
Mukti Yadav, Gurgaon, IN;
Vijay Kumar Kyama, Gurgaon, IN;
Vikas Bhandari, Gurgaon, IN;
Dhiraj Khattar, Gurgaon, IN;
Rajesh Khanna, Gurgaon, IN;
Sanjay Motwani, Gurgaon, IN;
Minakshi Garg, Gurgaon, IN;
Vikas Chandel, Gurgaon, IN;
Mukti Yadav, Gurgaon, IN;
Vijay Kumar Kyama, Gurgaon, IN;
Vikas Bhandari, Gurgaon, IN;
Fresenius Kabi Oncology Limited, New Delhi, IN;
Abstract
The present invention relates to a process of preparing a stable pharmaceutical composition of compounds which are susceptible to hydrolysis comprising a. Addition of required quantity of pharmaceutically acceptable lyophilization excipients optionally in Water for Injection in a formulation vessel; b. Addition of organic solvent to form a appropriate proportion of aqueous and organic solvent; c. Maintaining the temperature of the formulation vessel from the range −5±1° C. to −5±3° C.; d. Addition of required quantity of compound susceptible to hydrolysis to form a solution and lyophilizing the solution.