The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 2018
Filed:
Apr. 22, 2016
Applicant:
Abbvie Inc., North Chicago, IL (US);
Inventors:
Steven Elmore, Northbrook, IL (US);
Andrew Souers, Evanston, IL (US);
Lichun Wang, North Grafton, MA (US);
Tariq Ghayur, Holliston, MA (US);
Stuart J. Perper, Bellingham, MA (US);
Assignee:
AbbVie Inc., North Chicago, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/497 (2006.01); A61K 31/5377 (2006.01); A61K 31/496 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 31/496 (2013.01);
Abstract
This invention pertains to methods of treating systemic lupus erythematosus and Sjogren's Syndrome with compounds that selectively inhibit the activity of Bcl-2 anti-apoptotic proteins. Specifically, the current invention is directed to treatment with compounds that selectively inhibit the activity of Bcl-2 proteins, with a lesser affinity for inhibiting the activity of other BCL-2 family proteins, including Bcl-X.