The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 2018
Filed:
Sep. 02, 2015
Applicant:
Nusirt Sciences, Inc., Nashville, TN (US);
Inventors:
Michael Zemel, Knoxville, TN (US);
Antje Bruckbauer, Knoxville, TN (US);
Assignee:
NuSirt Sciences, Inc., Nashville, TN (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/198 (2006.01); A61K 45/06 (2006.01); A61K 31/05 (2006.01); A61K 31/155 (2006.01); A61K 31/352 (2006.01); A61K 31/4439 (2006.01); A61K 31/4985 (2006.01); A61K 31/519 (2006.01); A61K 31/53 (2006.01); A61K 31/522 (2006.01); A61K 31/7048 (2006.01);
U.S. Cl.
CPC ...
A61K 31/198 (2013.01); A61K 31/05 (2013.01); A61K 31/155 (2013.01); A61K 31/352 (2013.01); A61K 31/4439 (2013.01); A61K 31/4985 (2013.01); A61K 31/519 (2013.01); A61K 31/522 (2013.01); A61K 31/53 (2013.01); A61K 31/7048 (2013.01); A61K 45/06 (2013.01);
Abstract
Methods useful for reducing or preventing non-alcoholic steatohepatitis or hepatic steatosis are provided herein. Such methods may comprise administering to a subject in need thereof a sirtuin pathway activator and/or PDE5 inhibitor alone or in combination with an amount of a branched amino acid in free amino acid form, or a metabolite thereof. Also provided herein are compositions and kits for practicing any of the methods described herein.