The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 23, 2018
Filed:
Jul. 03, 2014
Applicants:
B Cell Design, Limoges, FR;
Universite DE Limoges, Limoges, FR;
Inventors:
Michel Cogne, Isles, FR;
Brice Laffleur, Limoges, FR;
Armelle Cuvillier, Saint-Jouvent, FR;
Marie Bosselut, Condar-sur-Vienne, FR;
Assignees:
B CELL DESIGN, Limoges, FR;
UNIVERSITE DE LIMOGES, Limoges, FR;
Primary Examiner:
Int. Cl.
CPC ...
A01K 67/00 (2006.01); C12P 21/00 (2006.01); A01K 67/027 (2006.01); C07K 16/00 (2006.01);
U.S. Cl.
CPC ...
A01K 67/0278 (2013.01); C07K 16/00 (2013.01); A01K 2217/072 (2013.01); A01K 2217/15 (2013.01); A01K 2217/206 (2013.01); A01K 2227/105 (2013.01); A01K 2267/01 (2013.01); C07K 2317/24 (2013.01); C12N 2800/30 (2013.01); C12N 2800/80 (2013.01);
Abstract
The invention relates to a transgenic non-human mammal comprising human immunoglobulin mu and epsilon heavy-chain constant transgenes Cμ and Cε inserted in place of endogenous mu heavy-chain switch sequence Sμ, and its use for producing chimeric human immunoglobulin E antibodies specific for an antigen of interest.