The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 16, 2018
Filed:
Apr. 30, 2015
Yufeng Jane Tseng, Stafford, VA (US);
National Taiwan University, Taipei, TW;
National Chiao Tung University, Hsinchu, TW;
National Health Research Institutes, Miaoli County, TW;
Yufeng Jane Tseng, Stafford, VA (US);
Yu-Li Liu, Miaoli County, TW;
Chung-Ming Sun, Hsinchu, TW;
Hai-Gwo Hwu, Taipei, TW;
Chih-Min Liu, Taipei, TW;
Wen-Sung Lai, Taipei, TW;
Other;
National Taiwan University, Taipei, TW;
National Chiao Tung University, Hsinchu, TW;
National Health Research Institutes, Miaoli County, TW;
Abstract
The invention utilizes virtual screening strategy to seek for current market drugs as anti-schizophrenia therapy drug repurposing. Drug repurposing strategy finds new uses other than the original medical indications of existing drugs. Finding new indications for such drugs will benefit patients who are in needs for a potential new therapy sooner since known drugs are usually with acceptable safety and pharmacokinetic profiles. In this study, repurposing marketed drugs for DAAO inhibitor as new schizophrenia therapy was performed with virtual screening on marketed drugs and its metabolites. The identified and available drugs and compounds were further confirmed with in vitro DAAO enzymatic inhibitory assay.