The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 16, 2018
Filed:
Jul. 07, 2013
Applicant:
Sirnaomics, Inc., Gaithersburg, MD (US);
Inventors:
Patrick Y. Lu, Potomac, MD (US);
David M. Evans, North Potomac, MD (US);
John J. Xu, Germantown, MD (US);
Alan Y. Lu, Baltimore, MD (US);
Qing Ge, Gaithersburg, MD (US);
Assignee:
Sirnaomics, Inc., Gaithersburg, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/11 (2006.01); C12N 15/113 (2010.01); A61K 9/00 (2006.01); A61K 31/713 (2006.01);
U.S. Cl.
CPC ...
C12N 15/1131 (2013.01); A61K 9/007 (2013.01); A61K 31/713 (2013.01); C12N 2310/14 (2013.01); C12N 2310/17 (2013.01); C12N 2320/11 (2013.01); C12N 2320/31 (2013.01); C12N 2320/32 (2013.01);
Abstract
The present invention relates to compositions and methods for development of resistance-proof siRNA therapeutics for prevention and treatment of influenza viral infections. The compositions include a pharmaceutical composition comprising siRNA molecules that target conserved regions of an influenza virus gene and a pharmaceutically acceptable polymeric carrier. In one embodiment, the polymeric carrier condenses the molecules to form a nanoparticle.