The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 16, 2018

Filed:

Apr. 24, 2013
Applicant:

Crioestaminal, Saúde E Tecnologia, Sa., Cantanhede, PT;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 5/0789 (2010.01); A61K 47/42 (2017.01); A61K 47/24 (2006.01); A61K 9/06 (2006.01); A01N 1/02 (2006.01); A61K 35/28 (2015.01);
U.S. Cl.
CPC ...
C12N 5/0647 (2013.01); A01N 1/0226 (2013.01); A61K 9/06 (2013.01); A61K 35/28 (2013.01); A61K 47/24 (2013.01); A61K 47/42 (2013.01); C12N 2500/02 (2013.01); C12N 2500/36 (2013.01); C12N 2501/999 (2013.01); C12N 2533/56 (2013.01);
Abstract

The present disclosure describes a method and composition for enhancing the survival of hematopoietic stem cells, preferably CD34+ derived from human umbilical cord or peripheral blood, in hypoxic and serum-deprived conditions by cultivating the cells in medium containing lysophosphatidic acid, preferably further comprising a gel, namely a biomimetic gel. The method and composition may be used in medicine or cosmetic application, in particular, in treatment of cardiac tissue and/or cardiac diseases, and/or in the treatment of wound healing namely diabetic wound healing.


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