The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 16, 2018
Filed:
Jun. 18, 2013
Applicants:
Indiana University Research and Technology Corporation, Indianapolis, IN (US);
Hoffmann-la Roche Inc., Little Falls, NJ (US);
Inventors:
Richard D. Dimarchi, Carmel, IN (US);
David L. Smiley, Bloomington, IN (US);
Konrad H. Bleicher, Freiburg i. Br., DE;
Eric A. Kitas, Aesch Baselland, CH;
Assignee:
Indiana University Research and Technology Corporation, Indianapolis, IN (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/26 (2006.01); A61K 38/28 (2006.01); A61K 38/00 (2006.01); A61P 3/10 (2006.01); A61P 7/12 (2006.01); C07K 14/605 (2006.01); C07K 5/00 (2006.01); C07K 7/00 (2006.01); C07K 16/00 (2006.01); C07K 17/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/605 (2013.01); A61K 38/26 (2013.01);
Abstract
Provided herein are glucagon analogs which exhibit potent activity at the GIP receptor, and, as such are contemplated for use in treating diabetes and obesity. In exemplary embodiments, the glucagon analog of the present disclosures exhibit an EC50 at the GIP receptor which is within the nanomolar or picomolar range.