The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 16, 2018

Filed:

Sep. 26, 2016
Applicant:

Epizyme, Inc., Cambridge, MA (US);

Inventors:

Kevin Wayne Kuntz, Woburn, MA (US);

Lorna Helen Mitchell, Cambridge, MA (US);

Gideon Shapiro, Gainesville, FL (US);

Richard Chesworth, Concord, MA (US);

Paula Ann Boriack-Sjodin, Lexington, MA (US);

Assignee:

Epizyme, Inc., Cambridge, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 231/12 (2006.01); A61K 31/415 (2006.01);
U.S. Cl.
CPC ...
C07D 231/12 (2013.01);
Abstract

Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds described herein are useful for inhibiting PRMT1 activity. Methods of using the compounds for treating PRMT1-mediated disorders are also described.


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