The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 16, 2018

Filed:

Aug. 31, 2015
Applicant:

The Regents of the University of California, Oakland, CA (US);

Inventors:

Sungho Jin, San Diego, CA (US);

Seunghan Oh, Iksan Jeonbuk, KR;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 49/00 (2006.01); A01N 63/00 (2006.01); A61F 2/00 (2006.01); C40B 60/12 (2006.01); A61L 27/30 (2006.01); A61L 27/38 (2006.01); A61L 27/54 (2006.01); A61L 27/10 (2006.01); A61L 27/14 (2006.01); A61L 27/16 (2006.01); A61L 27/18 (2006.01); C23C 28/00 (2006.01); C23C 30/00 (2006.01); C25D 7/00 (2006.01); C25D 11/02 (2006.01);
U.S. Cl.
CPC ...
A61L 27/306 (2013.01); A61L 27/10 (2013.01); A61L 27/14 (2013.01); A61L 27/16 (2013.01); A61L 27/18 (2013.01); A61L 27/30 (2013.01); A61L 27/3839 (2013.01); A61L 27/54 (2013.01); C23C 28/32 (2013.01); C23C 28/345 (2013.01); C23C 30/00 (2013.01); C25D 7/006 (2013.01); C25D 11/02 (2013.01); A61L 2300/252 (2013.01); A61L 2300/254 (2013.01); A61L 2300/256 (2013.01); A61L 2300/258 (2013.01); A61L 2300/406 (2013.01); A61L 2300/414 (2013.01); A61L 2300/43 (2013.01); A61L 2300/624 (2013.01); A61L 2400/12 (2013.01); A61L 2400/18 (2013.01);
Abstract

The present invention provides articles of manufacture comprising biocompatible nanostructures comprising significantly increased surface area for, e.g., organ, tissue and/or cell growth, e.g., for bone, tooth, kidney or liver growth, and uses thereof, e.g., for in vitro testing of drugs, chemicals or toxins, or as in vivo implants, including their use in making and using artificial tissues and organs, and related, diagnostic, screening, research and development and therapeutic uses, e.g., as drug delivery devices. The present invention provides biocompatible nanostructures with significantly increased surface area, such as with nanotube and nanopore array on the surface of metallic, ceramic, or polymer materials for enhanced cell and bone growth, for in vitro and in vivo testing, cleansing reaction, implants and therapeutics. The present invention provides optically transparent or translucent cell-culturing substrates. The present invention provides biocompatible and cell-growth-enhancing culture substrates comprising elastically compliant protruding nanostructure substrates coated with Ti, TiOor related metal and metal oxide films.


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