The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 16, 2018

Filed:

Jan. 22, 2016
Applicant:

Vanderbilt University, Nashville, TN (US);

Inventors:

Eric P. Skaar, Brentwood, TN (US);

Matthew Surdel, Nashville, TN (US);

Gary A. Sulikowski, Brentwood, TN (US);

Brendan Dutter, Nashville, TN (US);

Paul Reid, Durham, NC (US);

Alex Waterson, Murfreesboro, TN (US);

Assignee:

Vanderbilt University, Nashville, TN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 41/00 (2006.01); C07D 405/04 (2006.01); C07D 409/04 (2006.01); C07D 231/12 (2006.01); C12Q 1/18 (2006.01); C12N 9/02 (2006.01); C12Q 1/68 (2006.01); A61N 5/06 (2006.01);
U.S. Cl.
CPC ...
A61K 41/0057 (2013.01); C07D 231/12 (2013.01); C07D 405/04 (2013.01); C07D 409/04 (2013.01); C12N 9/001 (2013.01); C12Q 1/689 (2013.01); A61N 5/062 (2013.01); A61N 5/0624 (2013.01); C12Q 2600/136 (2013.01); C12Q 2600/156 (2013.01); C12Y 103/03004 (2013.01);
Abstract

A method for treating a microbial infection involves administering an effective amount of a compound of the formula: wherein Ris H, alkyl, aryl, heteroaryl, Ris H, halogen, alkyl, aryl, heteroaryl, Ris H, hydroxyl, alkoxy, alkyl, aryl, heteroaryl, amino, amino sulfonyl, acetamide, Ris H, hydroxyl, alkoxy, alkyl, aryl, heteroaryl, amino, amino sulfonyl, acetamide, Ris H, hydroxyl, alkoxy, alkyl, aryl, heteroaryl, amino, amino sulfonyl, acetamide, Ris H, hydroxyl, alkoxy, alkyl, aryl, heteroaryl, amino, amino sulfonyl, acetamide, Ris H, hydroxyl, alkoxy, alkyl, aryl, heteroaryl, amino, amino sulfonyl, acetamide, Ris —CR, O, S, wherein Rand R, Rand R, Rand R, Rand Rcan cyclize forming a 3-10 member ring comprising C, O, S, and/or N optionally substituted with one or more R; and administering light therapy, such as a photodynamic therapy (PDT) light source.


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