The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2018
Filed:
May. 30, 2014
Applicant:
Nektar Therapeutics, San Francisco, CA (US);
Inventors:
Ute Hoch, San Francisco, CA (US);
Christine Taylor Brew, Pacifica, CA (US);
Stephen David Harrison, Albany, CA (US);
Dennis G. Fry, Pacifica, CA (US);
Darren W. Davis, Houston, TX (US);
Assignee:
Other;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 33/573 (2006.01); G01N 33/574 (2006.01); G01N 33/68 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
G01N 33/573 (2013.01); A61K 47/48215 (2013.01); G01N 33/574 (2013.01); G01N 33/68 (2013.01); G01N 2333/99 (2013.01); G01N 2500/10 (2013.01); G01N 2800/52 (2013.01);
Abstract
Provided herein are methods directed to the prediction and early assessment of the efficacy of cancer treatment regimens, in particular in patients undergoing therapy with a DNA-damaging chemotherapeutic agent, by determining expression levels of certain proteins found to be useful as biomarkers in circulating tumor cells obtained from the patient both prior to and post-treatment.