The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 09, 2018

Filed:

May. 28, 2014
Applicant:

Daiichi Sankyo Company, Limited, Chuo-ku, Tokyo, JP;

Inventor:

Kenji Murakami, Tokyo, JP;

Assignee:

Daiichi Sankyo Company, Limited, Chuo-ku, Tokyo, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/85 (2006.01); C12P 21/00 (2006.01); C12P 21/02 (2006.01); C07K 16/00 (2006.01); C07K 16/18 (2006.01); C07K 14/47 (2006.01); C12N 15/63 (2006.01);
U.S. Cl.
CPC ...
C12N 15/85 (2013.01); C07K 14/47 (2013.01); C07K 16/00 (2013.01); C07K 16/18 (2013.01); C12N 15/63 (2013.01); C12P 21/00 (2013.01); C12P 21/02 (2013.01); C07K 2317/24 (2013.01); C12N 2830/85 (2013.01);
Abstract

The present invention relates to a transfected mammalian host cell whose ability to secrete a foreign protein has been enhanced by using a foreign gene expression vector having a promoter derived from a human gene, and a method for producing the foreign protein using the host cell. A method for enhancing the production of a foreign protein to be used in a pharmaceutical protein product in a host cell such as a cultured mammalian cell is provided. A promoter derived from a human gene having a promoter activity higher than that of a cytomegalovirus (CMV) promoter in a host cell such as a cultured mammalian cell is provided.


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