The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 09, 2018

Filed:

Jan. 21, 2011
Applicants:

Jacques F. Banchereau, Dallas, TX (US);

Monica Montes, Dallas, TX (US);

Anna Karolina Palucka, Dallas, TX (US);

Louis M. Sloan, Dallas, TX (US);

Yves Levy, Paris, FR;

Inventors:

Jacques F. Banchereau, Dallas, TX (US);

Monica Montes, Dallas, TX (US);

Anna Karolina Palucka, Dallas, TX (US);

Louis M. Sloan, Dallas, TX (US);

Yves Levy, Paris, FR;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/21 (2006.01); C12N 5/0784 (2010.01); C07K 14/005 (2006.01); A61K 39/12 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0639 (2013.01); A61K 39/12 (2013.01); A61K 39/21 (2013.01); C07K 14/005 (2013.01); A61K 2039/5154 (2013.01); A61K 2039/545 (2013.01); A61K 2039/6018 (2013.01); C12N 2501/052 (2013.01); C12N 2501/22 (2013.01); C12N 2501/24 (2013.01); C12N 2740/16222 (2013.01); C12N 2740/16234 (2013.01); C12N 2740/16322 (2013.01); C12N 2740/16334 (2013.01);
Abstract

Compositions and methods for the prophylaxis and treatment of human immunodeficiency virus (HIV) infections are disclosed herein. More specifically the present invention discloses describes an autologous dendritic cell (DC) vaccine product derived by culturing a patient's monocytes with granulocyte macrophage colony stimulating factor (GM-CSF) and interferon alpha 2b (IFN-α), loading the DC with a mixture of five lipopeptides of Gag, Nef and Pol HIV antigens, and, optionally activating the DC with lipopolysaccharide (LPS).


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