The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 09, 2018

Filed:

May. 28, 2014
Applicants:

Vib Vzw, Ghent, BE;

Life Sciences Research Partners Vzw, Leuven, BE;

Katholieke Universiteit Leuven, K.u.leuven R&d, Leuven, BE;

Inventors:

Wim Robberecht, Kumtich, BE;

Frederic Rousseau, Sint-Martens-Bodegem, BE;

Joost Schymkowitz, Meensel-Kiezegem, BE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/40 (2006.01); A61K 39/395 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/40 (2013.01); A61K 2039/505 (2013.01); C07K 2317/22 (2013.01); C07K 2317/569 (2013.01); C07K 2317/76 (2013.01); C07K 2317/77 (2013.01); C07K 2317/92 (2013.01); C07K 2319/21 (2013.01); C07K 2319/41 (2013.01); C07K 2319/42 (2013.01);
Abstract

The present application relates to the field of single-domain antibodies (also called nanobodies), more particularly single-domain antibodies against SOD1 protein isoforms. It also relates to the use of these nanobodies in medicine. Accordingly, methods to treat a disease using these nanobodies are provided herein. The single-domain antibodies are particularly envisaged for treatment of ALS.


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