The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2018
Filed:
Mar. 15, 2016
Applicant:
Bristol-myers Squibb Company, Princeton, NJ (US);
Inventors:
Yan Chen, Lexington, MA (US);
Elena Getmanova, Lexington, MA (US);
Martin C. Wright, Belmont, MA (US);
Alan S. Harris, Andover, MA (US);
Ai Ching Lim, Mercer Island, WA (US);
Jochem Gokemeijer, Wayland, MA (US);
Lin Sun, West Roxbury, MA (US);
Michael Wittekind, Bainbridge Island, WA (US);
Assignee:
BRISTOL-MYERS QUIBB COMPANY, Princeton, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/78 (2006.01); C07H 21/04 (2006.01); C12N 15/09 (2006.01); C07K 19/00 (2006.01); C07K 14/47 (2006.01); C07K 14/52 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); A61K 38/39 (2006.01); A61K 38/00 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/78 (2013.01); C07H 21/04 (2013.01); C07K 14/4703 (2013.01); C07K 14/52 (2013.01); C07K 16/2863 (2013.01); C07K 16/30 (2013.01); C07K 19/00 (2013.01); C12N 15/09 (2013.01); A61K 38/00 (2013.01); A61K 38/39 (2013.01); A61K 2039/505 (2013.01); C07K 2317/34 (2013.01); C07K 2317/73 (2013.01); C07K 2317/92 (2013.01); C07K 2318/20 (2013.01);
Abstract
The present disclosure relates to novel vascular endothelial growth factor receptor (VEGFR)-binding polypeptides and methods for using these polypeptides to inhibit biological activities mediated by vascular endothelial growth factors (VEGFs). The present disclosure also provides various improvements relating to single domain binding polypeptides.