The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2018
Filed:
Feb. 23, 2015
Applicants:
Prochon Biotech Ltd., Ness Ziona, IL;
Hepacore Ltd., Ness Ziona, IL;
Inventors:
Avner Yayon, Moshav Sitria, IL;
Eran Rom, Rehovot, IL;
Irina Chumakov, Rehovot, IL;
Sara Blumenstein, Ramat Gan, IL;
Assignees:
PROCHON BIOTECH LTD., Ness Ziona, IL;
HEPACORE LTD, Ness Ziona, IL;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/50 (2006.01); A61K 38/18 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/503 (2013.01); A61K 38/1825 (2013.01); C07K 14/50 (2013.01); A61K 38/00 (2013.01);
Abstract
The present invention relates to the design, manufacture and use of fibroblast growth factor (FGF) polypeptides having improved receptor specificity. In particular, the invention relates to isolated FGF2 polypeptides comprising a truncated N-terminus and optionally N-terminal amino acid substitutions. The present invention provides polypeptides, nucleic acids encoding the polypeptides, compositions comprising same and methods for use thereof.