The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2018
Filed:
Jul. 31, 2014
Amgen Inc., Thousand Oaks, CA (US);
Yumei Xiong, Palo Alto, CA (US);
Yi Zhang, Dublin, CA (US);
Jackie Z. Sheng, Thousand Oaks, CA (US);
Agnes Eva Hamburger, Newbury Park, CA (US);
Murielle Veniant-Ellison, Thousand Oaks, CA (US);
Grant Shimamoto, Westlake Village, CA (US);
Xiaoshan Min, Burlingame, CA (US);
Zhulun Wang, Palo Alto, CA (US);
Jie Tang, Palo Alto, CA (US);
Gunasekaran Kannan, Daly City, CA (US);
Marissa Mock, Newbury Park, CA (US);
Kenneth Walker, Newbury Park, CA (US);
Amgen Inc., Thousand Oaks, CA (US);
Abstract
Constructs comprising GDF15, and mutants thereof are provided. In various embodiments the constructs comprising GDF15, and mutants thereof, can be of use in the treatment or ameliorating a metabolic disorder. In various embodiments the metabolic disease or disorder is type 2 diabetes, obesity, dyslipidemia, elevated glucose levels, elevated insulin levels and diabetic nephropathy.