The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 09, 2018
Filed:
Jan. 06, 2017
Applicant:
Broadpharm, San Diego, CA (US);
Inventors:
Hanzhong Zhang, San Diego, CA (US);
Hongyuan Chen, Irvine, CA (US);
Mikhail Kondratenko, San Diego, CA (US);
Si Wang, San Diego, CA (US);
Qiwen Zhong, Temecula, CA (US);
Assignee:
BROADPHARM, San Diego, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07D 209/08 (2006.01); C07D 403/14 (2006.01); C07D 495/04 (2006.01); C07D 417/06 (2006.01); A61K 49/00 (2006.01); C09B 69/10 (2006.01); C09K 11/06 (2006.01);
U.S. Cl.
CPC ...
C07D 209/08 (2013.01); A61K 49/0032 (2013.01); A61K 49/0052 (2013.01); A61K 49/0054 (2013.01); C07D 403/14 (2013.01); C07D 417/06 (2013.01); C07D 495/04 (2013.01); C09B 69/105 (2013.01); C09K 11/06 (2013.01); C09K 2211/14 (2013.01);
Abstract
Provided herein are functionalized pegylated cyanine compounds containing a reactive group suitable for labeling a biomolecule or pharmaceutical compositions and methods of use thereof. In one embodiment, the compounds are based on formula I shown below. In other embodiments, the compounds can be pegylated at one or more of the following locations R, R, R, R, or L.