The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 09, 2018

Filed:

May. 29, 2014
Applicant:

Rutgers, the State University of New Jersey, New Brunswick, NJ (US);

Inventors:

Kathryn Uhrich, New Brunswick, NJ (US);

Michelle Morano, New Brunswick, NJ (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 8/02 (2006.01); A61K 8/37 (2006.01); A61Q 17/04 (2006.01); C07C 69/734 (2006.01); C08G 63/06 (2006.01); C08G 63/66 (2006.01);
U.S. Cl.
CPC ...
C07C 69/734 (2013.01); A61K 8/025 (2013.01); A61K 8/37 (2013.01); A61Q 17/04 (2013.01); C08G 63/06 (2013.01); C08G 63/66 (2013.01);
Abstract

Certain embodiments of the invention provide antioxidant-based diacids and polymers comprising glycol groups as described herein, and methods of use thereof. In certain embodiments the polymers described herein are formulated as microspheres or hydrogels. Described herein is the chemical incorporation of antioxidants, e.g., coumaric acid, ferulic acid, and sinapic acid, into a polymer backbone for use, e.g., in applications for localized release and rapid delivery. As provided, the chemical composition of the linker molecules used (of which hold together two bioactives via ester linkages) may be used to vary the hydrophilicity of the polymer. The bioactive release rate may also be altered for a tunable release delivery system, allowing for increased bioactive release compared to other linkers previously utilized.


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Uhrich, Kathryn. (2018). Antioxidant-based poly(anhydride-esters) (U.S. Patent No. 9862672). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9862672

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