The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 09, 2018

Filed:

Apr. 28, 2015
Applicant:

Pfizer Inc., New York, NY (US);

Inventors:

Patricia Ann Basford, Sandwich, GB;

Anthony Michael Campeta, Ledyard, CT (US);

Adam Gillmore, Sandwich, GB;

Matthew Cameron Jones, Sandwich, GB;

Eleftherios Kougoulos, Morrisville, NC (US);

Suman Luthra, Groton, CT (US);

Robert Walton, Sandwich, GB;

Assignee:

PFIZER INC., New York, NY (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/55 (2006.01); C07D 487/06 (2006.01); C07C 57/145 (2006.01); C07C 309/19 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/55 (2013.01); A61K 45/06 (2013.01); C07C 57/145 (2013.01); C07C 309/19 (2013.01); C07D 487/06 (2013.01);
Abstract

The present invention relates to novel polymorphic forms of 8-fluoro-2-{4-[(methylamino)methyl]phenyl}-1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one, and to processes for their preparation. Such polymorphic forms may be a component of a pharmaceutical composition and may be used to treat a mammalian disease condition mediated by poly(ADP-ribose) polymerase activity including the disease condition such as cancer.


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