The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 09, 2018

Filed:

May. 28, 2015
Applicant:

Access Closure, Inc., Santa Clara, CA (US);

Inventors:

Andreas Mylonakis, Santa Clara, CA (US);

Florencia Lim, Union City, CA (US);

Assignee:

ACCESS CLOSURE, INC., Santa Clara, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61B 17/08 (2006.01); A61D 1/00 (2006.01); A61B 17/00 (2006.01); A61L 24/00 (2006.01); A61L 24/08 (2006.01); A61L 31/04 (2006.01); A61L 31/06 (2006.01); A61L 31/14 (2006.01);
U.S. Cl.
CPC ...
A61B 17/0057 (2013.01); A61L 24/0031 (2013.01); A61L 24/08 (2013.01); A61L 31/042 (2013.01); A61L 31/06 (2013.01); A61L 31/145 (2013.01); A61L 31/148 (2013.01); A61B 2017/0065 (2013.01); A61B 2017/00623 (2013.01); A61L 2400/04 (2013.01);
Abstract

A sealant is provided for sealing a puncture through tissue that comprises an elongate first section including a proximal end, a distal end, and a cross-section sized for delivery into a puncture through tissue, and a second section extending from the distal end of the first section. The first section may be formed from a freeze-dried hydrogel that expands when exposed to physiological fluid within a puncture. The first section comprises chitosan and at least one additional polymer. The second section may be formed from a solid mass of non-freeze-dried, non-cross-linked hydrogel precursors. The precursors are in an unreactive state until exposed to an aqueous physiological environment, whereupon the precursors undergo in-situ crosslinking with one another to provide an adhesive layer bonded to the first section. The second section may further comprise chitosan. Apparatus and methods for delivering the sealant into a puncture through tissue are also provided.


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