The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 2018
Filed:
Apr. 01, 2016
Regents of the University of Minnesota, Minneapolis, MN (US);
Gregory J. Metzger, Lake Elmo, MN (US);
Stephen C. Schmechel, Seattle, WA (US);
Chaitanya Kalavagunta, Crofton, MD (US);
Joseph S. Koopmeiners, St. Paul, MN (US);
Christopher A. Warlick, Lake Elmo, MN (US);
Regents of the University of Minnesota, Minneapolis, MN (US);
Abstract
A user-independent, quantitative, multiparametric MRI model is developed and validated on co-registered correlative histopathology, yielding improved performance for cancer detection over single parameter estimators. A computing device may be configured to receive a first parametric map that maps imaged tissue of a patient using values of a first parameter, and a second parametric map that maps the imaged tissue using values of a second parameter, wherein the parametric maps are generated from medical imaging data for the imaged tissue. The computing device may be further configured to apply a multiparametric model to the maps to generate at least one Composite Biomarker Score for the tissue, the model being a function of the first parameter and the second parameter. The function may be determined based on co-registered histopathology data. The computing device may be further configured to generate an indication of whether the tissue includes predicted cancer, and output the indication.