The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 2018
Filed:
Oct. 25, 2011
Lynn Y. Sakai, Portland, OR (US);
Lynn M. Marshall, Portland, OR (US);
Eric J. Carlson, Portland, OR (US);
Noe L. Charbonneau, Portland, OR (US);
Susan J. Hayflick, Portland, OR (US);
Lynn Y. Sakai, Portland, OR (US);
Lynn M. Marshall, Portland, OR (US);
Eric J. Carlson, Portland, OR (US);
Noe L. Charbonneau, Portland, OR (US);
Susan J. Hayflick, Portland, OR (US);
SHRINERS HOSPITAL FOR CHILDREN, Tampa, FL (US);
Abstract
The present invention makes use of immunoassays, such as sandwich ELISAs, to profile the circulating concentration of elastic fiber and microfibril fragments in samples from individuals with diseases associated with elastic fiber and/or microfibril degradation. Examples of such diseases include, Marfan's syndrome, aortic aneurysm, and scleroderma. Profiling the concentration of such fragments can be used to diagnose disease and monitor disease progression.