The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2018

Filed:

May. 28, 2014
Applicant:

Denovo Sciences, Plymouth, MI (US);

Inventors:

Kalyan Handique, Ann Arbor, MI (US);

Priyadarshini Gogoi, Ann Arbor, MI (US);

Yi Zhou, Plymouth, MI (US);

Saedeh Sepehri, Ypsilanti, MI (US);

Christopher Siemer, Ypsilanti, MI (US);

Assignee:

DeNovo Sciences, Inc., Plymouth, MI (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 (2006.01); G01N 33/574 (2006.01); B01L 3/00 (2006.01); C12M 1/32 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6886 (2013.01); B01L 3/502761 (2013.01); C12Q 1/6834 (2013.01); C12Q 1/6841 (2013.01); G01N 33/57415 (2013.01); G01N 33/57423 (2013.01); B01L 2200/0668 (2013.01); B01L 2200/16 (2013.01); B01L 2300/087 (2013.01); B01L 2300/0819 (2013.01); B01L 2300/0867 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/086 (2013.01); C12M 23/12 (2013.01); G01N 2800/52 (2013.01);
Abstract

A system and method for isolating cells, comprising: a substrate having a broad surface; an array comprising a set of wells defined at the broad surface of the substrate, each well including: a base surface, an open surface directly opposing the base surface, defined at the broad surface of the substrate, and configured to receive one of a single cell and a single cluster of cells from a direction perpendicular to the broad surface of the substrate, and a set of channels that fluidly couple each well to at least one adjacent well; wherein the set of wells includes an interior subset and an exterior subset fluidly coupled to and surrounding the interior subset by way of the set of channels; and a fluid delivery module surrounding the array and fluidly coupled to each well in the set of wells.


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