The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 2018
Filed:
Feb. 28, 2013
Applicant:
Tissuse Gmbh, Berlin, DE;
Inventors:
Mark Rosowski, Berlin, DE;
Shirin Kadler, Berlin, DE;
Roland Lauster, Berlin, DE;
Uwe Marx, Spreenhagen, DE;
Assignee:
TISSUSE GMBH, Berlin, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/0775 (2010.01); C12N 5/071 (2010.01); C12N 5/0789 (2010.01); C12N 5/077 (2010.01); G01N 33/50 (2006.01); G01N 33/68 (2006.01); A61L 27/10 (2006.01); A61L 27/38 (2006.01); A61L 27/50 (2006.01); A61L 27/54 (2006.01); C12M 3/00 (2006.01); C12M 1/00 (2006.01);
U.S. Cl.
CPC ...
C12N 5/0697 (2013.01); A61L 27/10 (2013.01); A61L 27/3834 (2013.01); A61L 27/3847 (2013.01); A61L 27/3852 (2013.01); A61L 27/50 (2013.01); A61L 27/54 (2013.01); C12M 21/08 (2013.01); C12M 29/00 (2013.01); C12N 5/0647 (2013.01); C12N 5/0655 (2013.01); C12N 5/0663 (2013.01); G01N 33/502 (2013.01); G01N 33/5044 (2013.01); G01N 33/5088 (2013.01); G01N 33/6887 (2013.01); A61L 2300/64 (2013.01); A61L 2430/02 (2013.01); A61L 2430/06 (2013.01); C12N 2502/1171 (2013.01); C12N 2502/1311 (2013.01); C12N 2502/1317 (2013.01); C12N 2502/1358 (2013.01); C12N 2506/1353 (2013.01); C12N 2513/00 (2013.01); C12N 2533/14 (2013.01);
Abstract
A 3D in vitro bi-phasic cartilage-bone organoid includes a layer of an artificial cartilage tissue, and a layer of an artificial bone tissue comprising a structure-giving scaffold and a bone marrow structure. The layer of the artificial cartilage tissue contacts at least one surface of the layer of the artificial bone tissue.