The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2018

Filed:

Mar. 17, 2014
Applicants:

Xiamen University, Xiamen, CN;

The United States of America, As Represented BY the Secretary, Department of Health and Human Services, Washington, DC (US);

Xiamen Innovax Biotech Co., Ltd., Xiamen, CN;

Inventors:

Zizheng Zheng, Xiamen, CN;

Jason S. McLellan, Hanover, NH (US);

Man Chen, Bethesda, MD (US);

Min Zhao, Xiamen, CN;

Liangmin Huang, Xiamen, CN;

Barney S. Graham, Bethesda, MD (US);

Ningshao Xia, Xiamen, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/10 (2006.01); A61K 31/7084 (2006.01); C07K 14/005 (2006.01); A61K 39/155 (2006.01); C12N 7/00 (2006.01); A61K 39/12 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/1027 (2013.01); A61K 31/7084 (2013.01); A61K 39/155 (2013.01); C07K 14/005 (2013.01); C12N 7/00 (2013.01); A61K 39/12 (2013.01); A61K 2039/53 (2013.01); C07K 2317/20 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/34 (2013.01); C07K 2317/51 (2013.01); C07K 2317/54 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/622 (2013.01); C07K 2317/626 (2013.01); C07K 2317/76 (2013.01); C07K 2319/00 (2013.01); C07K 2319/35 (2013.01); C12N 2760/18522 (2013.01); C12N 2760/18534 (2013.01);
Abstract

The present invention relates to an epitope peptide (or a variant thereof) which can be used in the prevention of respiratory syncytial virus (RSV) infection, a recombinant protein comprising the epitope peptide (or a variant thereof) and a carrier protein, and uses of the epitope peptide (or a variant thereof) and the recombinant protein. The present invention also relates to an antibody against the epitope peptide, a cell line for generating the antibody, and uses thereof. Furthermore, the present invention also relates to a vaccine or a pharmaceutical composition comprising the recombinant protein or the antibody according to the invention, for preventing one or more symptoms associated with RSV infection.


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