The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 2018
Filed:
Oct. 10, 2014
Applicant:
University of Massachusetts, Boston, MA (US);
Inventors:
Jack L. Leonard, Shrewsbury, MA (US);
Deborah M. Leonard, Shrewsbury, MA (US);
Karl J. Simin, Princeton, MA (US);
Assignee:
University of Massachusetts, Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/86 (2006.01); A61K 48/00 (2006.01); A61K 38/00 (2006.01); C12N 15/00 (2006.01); C07K 14/47 (2006.01); A61K 38/17 (2006.01); A61K 35/76 (2015.01); A01K 67/027 (2006.01); C07K 14/82 (2006.01); C07K 14/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/4703 (2013.01); A01K 67/0276 (2013.01); A61K 35/76 (2013.01); A61K 38/1709 (2013.01); C07K 14/00 (2013.01); C07K 14/82 (2013.01); A01K 2217/075 (2013.01); A01K 2217/15 (2013.01); A01K 2217/203 (2013.01); A01K 2227/105 (2013.01); A01K 2267/0331 (2013.01); A01K 2267/0393 (2013.01); A61K 38/00 (2013.01); C07K 2319/10 (2013.01); C07K 2319/21 (2013.01); C12N 2740/15043 (2013.01);
Abstract
The invention relates to novel therapeutic approaches to cancer treatment that exploits tumor suppressor functions of DKK3b by site-specific delivery of DKK3b. Novel therapeutics and methods for treating tumors and cancers utilizing DKK3b tumor suppressor functions are disclosed.