The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2018

Filed:

Apr. 18, 2012
Applicants:

Kristiina Takkinen, Espoo, FI;

Marja-leena Laukkanen, Espoo, FI;

Hans Söderlund, Espoo, FI;

Sirpa Jylhä, Espoo, FI;

Heidi Holkeri, Espoo, FI;

Merja Niemi, Joensuu, FI;

Janne Jänis, Joensuu, FI;

Juha Rouvinen, Joensuu, FI;

Inventors:

Kristiina Takkinen, Espoo, FI;

Marja-Leena Laukkanen, Espoo, FI;

Hans Söderlund, Espoo, FI;

Sirpa Jylhä, Espoo, FI;

Heidi Holkeri, Espoo, FI;

Merja Niemi, Joensuu, FI;

Janne Jänis, Joensuu, FI;

Juha Rouvinen, Joensuu, FI;

Assignee:

DESENTUM OY, Helsinki, FI;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/35 (2006.01); A61K 39/36 (2006.01); C07K 1/00 (2006.01); C07K 14/00 (2006.01); C07K 17/00 (2006.01); C07K 14/415 (2006.01);
U.S. Cl.
CPC ...
C07K 14/415 (2013.01); A61K 39/36 (2013.01);
Abstract

The present invention provides mutant polypeptides useful as hypoallergens. More specifically the present invention provides mutant Bet v 1 proteins and the use of such polypeptides as hypoallergens for desensitizing against birch pollen allergies. Furthermore, the invention provides vaccine formulations comprising such polypeptides; the use of such formulations; and to methods of vaccination against birch pollen allergy.


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