The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2018

Filed:

Jun. 13, 2014
Applicants:

Biowintech, Paris, FR;

Commissariat a L'energie Atomique ET Aux Energies Alternatives (Cea), Paris, FR;

Inventors:

Guy Deniau, Les Essarts-le-Roi, FR;

Cedric Zobrist, Bures-sur-Yvette, FR;

Maxime Oudin, Paris, FR;

Laurent David, Paris, FR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 31/08 (2006.01); A61L 31/16 (2006.01); A61L 27/00 (2006.01); C07C 309/22 (2006.01); C07C 309/24 (2006.01); A61L 27/34 (2006.01); A61L 27/50 (2006.01); C07C 309/17 (2006.01); C07C 309/18 (2006.01);
U.S. Cl.
CPC ...
A61L 31/16 (2013.01); A61L 27/34 (2013.01); A61L 27/50 (2013.01); A61L 31/08 (2013.01); C07C 309/17 (2013.01); C07C 309/18 (2013.01); C07C 309/22 (2013.01); C07C 309/24 (2013.01); A61L 2300/21 (2013.01); A61L 2300/606 (2013.01); A61L 2420/02 (2013.01); A61L 2430/16 (2013.01);
Abstract

The present invention relates to an implantable material having at least one external surface grafted with a film including carboxylate and sulfonate functions wherein the film is simultaneously synthesized and grafted directly on the external surface by radical reaction of a bifunctional adhesion primer of Formula (I) or by radical reaction of an adhesion primer and a bifunctional polymerizable monomer of Formula (II). The invention also relates to a process for directly synthesizing and grafting of a film according to the invention onto at least one external surface of an implantable material. The invention further relates to the use of a grafted implantable material for the manufacture of an antiproliferative and/or antibacterial implantable medical device. The invention also relates to compounds of Formula (I) and Formula (II).


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