The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2018

Filed:

Apr. 15, 2016
Applicant:

Huazhong University of Science and Technology, Wuhan, CN;

Inventors:

Shengmin Zhang, Wuhan, CN;

Mingle Cai, Wuhan, CN;

Haoming Liu, Wuhan, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61L 27/18 (2006.01); A61L 27/22 (2006.01); A61L 27/54 (2006.01); A61L 27/58 (2006.01); A61L 27/56 (2006.01);
U.S. Cl.
CPC ...
A61L 27/18 (2013.01); A61L 27/222 (2013.01); A61L 27/54 (2013.01); A61L 27/56 (2013.01); A61L 27/58 (2013.01); A61L 2300/412 (2013.01); A61L 2300/604 (2013.01); A61L 2430/02 (2013.01);
Abstract

The invention discloses an energy-providing bone-repair degradable porous scaffold, a preparation method thereof, and an application thereof. The invention obtains an energy-based biomaterial solution by compositing gelatin, a polyatomic acid and derivatives thereof, a dibasic alcohol and derivatives thereof, and a tribasic alcohol and derivatives thereof in a chemical cross-linking manner by using diisocyanate, and further obtains a porous scaffold through a drying method. The porous scaffold can avoid the problem of an acidic microenvironment caused by in vivo implantation of the existing biomaterial and keep the activity of an osteoblast cell, thereby improving the rate of repairing the damaged bone tissue with the energy-based biomaterial. The porous scaffold of the invention can be used as a filling material for bone repair in a surgical operation.


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