The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 2018
Filed:
Jul. 17, 2015
Vrije Universiteit Brussel, Brussels, BE;
Nick Devoogdt, Eppegem-Zemst, BE;
Jens De Vos, Strombeek-Bever, BE;
Matthias D'Huyvetter, Wilrijk, BE;
Tony Lahoutte, Ganshoren, BE;
VRIJE UNIVERSITEIT BRUSSEL, Brussels, BE;
Abstract
The application provides polypeptides comprising or essentially consisting of at least one heavy chain variable domain of a heavy chain antibody (V) or functional fragments thereof, wherein said Vor functional fragment thereof specifically binds to a target protein that is present on and/or specific for a solid tumor or cancer cell, e.g., HER2. The application further provides nucleic acids encoding such polypeptides; methods for preparing such polypeptides; host cells expressing or capable of expressing such polypeptides; compositions, and in particular to pharmaceutical compositions that comprise such polypeptides, nucleic acids and/or host cells. The application further provides such polypeptides, nucleic acids, host cells and/or compositions, for use in methods for the prevention and/or treatment of cancer.