The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 2018
Filed:
Jan. 25, 2016
Applicant:
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Inventors:
Markus H. Frank, Cambridge, MA (US);
Natasha Y. Frank, Cambridge, MA (US);
Mohamed H. Sayegh, Westwood, MA (US);
Assignee:
The Brigham and Women's Hospital, Inc., Boston, MA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 47/48 (2006.01); C07K 16/18 (2006.01); A61K 31/713 (2006.01); A61K 38/47 (2006.01); C12N 15/113 (2010.01); G01N 33/574 (2006.01); A61K 47/68 (2017.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
A61K 47/48569 (2013.01); A61K 31/713 (2013.01); A61K 38/47 (2013.01); A61K 47/6851 (2017.08); C07K 16/18 (2013.01); C12N 15/1135 (2013.01); G01N 33/57492 (2013.01); A61K 2039/505 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); C12N 2310/14 (2013.01); C12N 2310/3513 (2013.01); C12N 2320/32 (2013.01); C12Y 302/02022 (2013.01); G01N 2333/705 (2013.01);
Abstract
The invention relates to methods for treating a subject by manipulating ABCB5 on a cell as well as related products. The methods include methods of treating cancer using ABCB5 binding molecules such as antibodies and fragments thereof.