The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2018

Filed:

Feb. 27, 2012
Applicants:

Jae Chan Kim, Seoul, KR;

Doo Hwan OH, Seoul, KR;

Kwang Sic Joo, Seoul, KR;

Yeoun Sook Chun, Seoul, KR;

Sung Wook Wee, Seoul, KR;

Kyoung Woo Kim, Seoul, KR;

Inventors:

Jae Chan Kim, Seoul, KR;

Doo Hwan Oh, Seoul, KR;

Kwang Sic Joo, Seoul, KR;

Yeoun Sook Chun, Seoul, KR;

Sung Wook Wee, Seoul, KR;

Kyoung Woo Kim, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/46 (2006.01); C07K 14/515 (2006.01); A61K 45/06 (2006.01); G01N 33/68 (2006.01); A61K 38/18 (2006.01);
U.S. Cl.
CPC ...
A61K 38/465 (2013.01); A61K 45/06 (2013.01); C07K 14/515 (2013.01); G01N 33/6863 (2013.01); A61K 38/1891 (2013.01); G01N 2333/52 (2013.01); G01N 2500/10 (2013.01);
Abstract

The present invention provides a pharmaceutical composition for the prevention or treatment of glaucoma, wherein the pharmaceutical composition includes angiogenin or a fragment thereof as an active ingredient. Angiogenin or a fragment thereof according to the present invention activates aqueous humor outflow due to NO generation increase, Schlemm's canal expansion, and intercellular interval widening, thereby reducing intraocular pressure. Accordingly, angiogenin and a fragment may be useful for the prevention and treatment of glaucoma.


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