The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2018

Filed:

Apr. 27, 2016
Applicant:

Reflex Medical, Inc., Los Altos Hills, CA (US);

Inventor:

Corinne Bright, Los Altos Hills, CA (US);

Assignee:

Reflex Medical, Inc., Los Altos Hills, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/21 (2006.01); A61K 45/06 (2006.01); A61K 31/55 (2006.01); A61B 18/14 (2006.01); A61B 8/08 (2006.01); A61N 5/02 (2006.01); A61N 7/02 (2006.01); A61B 90/30 (2016.01); A61B 17/34 (2006.01); A61B 8/12 (2006.01); A61B 18/18 (2006.01); A61K 31/4422 (2006.01); A61K 31/475 (2006.01); A61B 18/00 (2006.01);
U.S. Cl.
CPC ...
A61K 38/217 (2013.01); A61B 8/12 (2013.01); A61B 17/3403 (2013.01); A61B 18/1492 (2013.01); A61B 18/1815 (2013.01); A61B 90/30 (2016.02); A61K 31/4422 (2013.01); A61K 31/475 (2013.01); A61K 31/55 (2013.01); A61K 45/06 (2013.01); A61N 5/022 (2013.01); A61N 7/02 (2013.01); A61B 8/0808 (2013.01); A61B 2017/3413 (2013.01); A61B 2018/0022 (2013.01); A61B 2018/00023 (2013.01); A61B 2018/0044 (2013.01); A61B 2018/00434 (2013.01); A61B 2018/00577 (2013.01); A61B 2018/1861 (2013.01); A61B 2018/1869 (2013.01); A61B 2090/306 (2016.02);
Abstract

Methods, devices and systems are described for decreasing the activity of the sympathetic nervous innervation to and from the lungs and the vessels supplying the lungs to treat pulmonary medical conditions such as asthma. In one embodiment, the method may involve advancing an intravascular instrument to a target location in a blood vessel within the intercostal vasculature to ablate either or both the sympathetic afferent and efferent nerves lying within the paravertebral gutter including the visceral fibers that travel to the cardiothoracic cavity and abdominopelvic viscera and the T1 to T4/5 sympathetic chain. In another embodiment, an intravascular instrument may be advanced to the bronchial vessels to ablate either or both the sympathetic afferent and efferent nerves in and around the posterior pulmonary plexus. In one embodiment the ablative agent is a neurolytic agent delivered in a gel. This approach may be utilized to treat other cardiac and pulmonary diseases.


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