The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2018

Filed:

Mar. 12, 2015
Applicant:

Genentech, Inc., South San Francisco, CA (US);

Inventors:

Jeffrey J. Hager, San Diego, CA (US);

James D. Joseph, San Diego, CA (US);

Jing Qian, San Diego, CA (US);

Nicholas D. Smith, San Diego, CA (US);

Edna Chow Maneval, San Diego, CA (US);

Debasish F. Roychowdhury, San Diego, CA (US);

Lori Friedman, San Carlos, CA (US);

Deepak Sampath, San Francisco, CA (US);

Assignee:

GENENTECH, INC., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5375 (2006.01); A61K 31/416 (2006.01); A61K 31/4245 (2006.01); A61K 31/428 (2006.01); A61K 31/437 (2006.01); A61K 31/4025 (2006.01); A61K 31/397 (2006.01); C12Q 1/68 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5375 (2013.01); A61K 31/397 (2013.01); A61K 31/4025 (2013.01); A61K 31/416 (2013.01); A61K 31/428 (2013.01); A61K 31/4245 (2013.01); A61K 31/437 (2013.01); C12Q 1/6886 (2013.01); C12Q 2600/156 (2013.01);
Abstract

Described herein are methods and compositions for treating an ER-related disease condition characterized by a mutation in the ESR1 gene by administering an estrogen receptor modulator. Also described herein are methods of treating hormone resistant-estrogen receptor (ER) positive breast cancers characterized by a mutation in the ESR1 gene by administering an estrogen receptor modulator.


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