The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2018

Filed:

Jun. 01, 2016
Applicant:

Grünenthal Gmbh, Aachen, DE;

Inventors:

Klaus Wening, Köln, DE;

Anja Geiβler, Karlsruhe, DE;

Jana Denker, Bornheim, DE;

Lutz Barnscheid, Mönchengladbach, DE;

Assignee:

GRÜNENTHAL GMBH, Aachen, DE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 9/50 (2006.01); A61K 31/485 (2006.01); A61K 9/16 (2006.01); A61K 9/20 (2006.01); A61K 9/48 (2006.01); A61K 31/137 (2006.01);
U.S. Cl.
CPC ...
A61K 31/485 (2013.01); A61K 9/1611 (2013.01); A61K 9/1617 (2013.01); A61K 9/1635 (2013.01); A61K 9/1641 (2013.01); A61K 9/1652 (2013.01); A61K 9/1658 (2013.01); A61K 9/1694 (2013.01); A61K 9/2077 (2013.01); A61K 9/4808 (2013.01); A61K 9/50 (2013.01); A61K 31/137 (2013.01);
Abstract

A tamper-resistant pharmaceutical dosage form comprising a multitude of particles which comprise a pharmacologically active compound, a polyalkylene oxide, and a disintegrant; wherein the pharmacologically active compound is dispersed in a matrix comprising the polyalkylene oxide and the disintegrant; wherein the content of the disintegrant is more than 5.0 wt.-%, based on the total weight of the pharmaceutical dosage form and/or based on the total weight of the particles; wherein the content of the polyalkylene oxide is at least 25 wt.-%, based on the total weight of the pharmaceutical dosage form and/or based on the total weight of the particles; and wherein the dosage form provides under in vitro conditions immediate release of the pharmacologically active compound in accordance with Ph. Eur.


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