The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 2018
Filed:
Oct. 31, 2013
Applicant:
Nippon Kayaku Kabushiki Kaisha, Chiyoda-ku, Tokyo, JP;
Inventors:
Keiichiro Yamamoto, Tokyo, JP;
Manami Okazaki, Tokyo, JP;
Assignee:
Nippon Kayaku Kabushiki Kaisha, Tokyo, JP;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4745 (2006.01); A61K 31/551 (2006.01); A61K 31/55 (2006.01); A61K 31/765 (2006.01); A61K 31/4184 (2006.01); A61K 47/48 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4745 (2013.01); A61K 31/4184 (2013.01); A61K 31/55 (2013.01); A61K 31/551 (2013.01); A61K 31/765 (2013.01); A61K 47/48215 (2013.01); A61K 47/48315 (2013.01);
Abstract
The purpose of the present invention is to provide a polymeric compound in which a camptothecin compound and an anti-cancer effect enhancer, particularly a PARP inhibitor, are bound to a single molecule, whereby it becomes possible to reduce the toxicity to normal cells and deliver and release the two components to an affected area with high efficiency to thereby improve the pharmacological efficacy of the two components. Provided is a polymeric compound represented by general formula (1).