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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9855251 B1

PDFFull Text
Date of Patent:
Jan. 02, 2018

Filed:

Feb. 11, 2016

Use of metformin in combination with a glucokinase activator and compositions comprising metformin and a glucokinase activator

Applicant:

Vtv Therapeutics Llc, High Point, NC (US);

Inventors:

Adnan M. M. Mjalli, Oak Ridge, NC (US);

Maria Carmen Valcarce Lopez, Oak Ridge, NC (US);

Assignee:

vTv Therapeutics LLC, High Point, NC (US);

Attorney:

Samuel B. Rollins

Primary Examiner:

Svetlana M Ivanova

Int. Cl.
CPC ...
A61K 31/425 (2006.01); A61K 31/155 (2006.01); A61K 31/426 (2006.01); C07D 277/54 (2006.01);
U.S. Cl.
CPC ...
A61K 31/426 (2013.01); A61K 31/155 (2013.01); C07D 277/54 (2013.01);
Abstract

The present invention provides uses of a glucokinase activator in combination with metformin. Uses include treating type 2 diabetes, lowering blood glucose, improving insulin sensitivity, enhancing phosphorylation of glucose, and improving the therapeutic effectiveness of metformin. The invention also provides pharmaceutical compositions that comprise a GK activator and metformin. The invention also provides a salt formed between metformin and a GK activator.

Find Patent Forward Citations

Mjalli, Adnan M. M.. (2018). Use of metformin in combination with a glucokinase activator and compositions comprising metformin and a glucokinase activator (U.S. Patent No. 9855251). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/9855251

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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