The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 2018
Filed:
Apr. 30, 2014
Applicant:
Abbvie Inc., North Chicago, IL (US);
Inventors:
Blas Coll Crespo, Highland Park, IL (US);
Dennis Andress, Chicago, IL (US);
John J. Brennan, Libertyville, IL (US);
James C. Stolzenbach, Buffalo Grove, IL (US);
Assignee:
AbbVie Inc., North Chicago, IL (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 31/4025 (2006.01); A61K 45/06 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4025 (2013.01); A61K 45/06 (2013.01);
Abstract
The present disclosure is directed to methods for reducing cardiovascular risk in a human subject by administering atrasentan, or a pharmaceutically acceptable salt thereof, in an amount sufficient to effect a reduction of about 5% or more in one or both of (a) total serum cholesterol, relative to the subject's baseline total serum cholesterol, and (b) serum LDL cholesterol, relative to the subject's baseline serum LDL cholesterol.