The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jan. 02, 2018
Filed:
Jul. 26, 2016
Applicant:
University of Washington, Seattle, WA (US);
Inventors:
Tadao Maeda, Mayfield Heights, OH (US);
David Saperstein, Seattle, WA (US);
Krzysztof Palczewski, Bay Village, OH (US);
Assignee:
University of Washington, Seattle, WA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/07 (2006.01); A61K 31/215 (2006.01); A61K 31/4709 (2006.01); A61K 31/22 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/215 (2013.01); A61K 9/0053 (2013.01); A61K 31/07 (2013.01); A61K 31/22 (2013.01); A61K 31/4709 (2013.01); Y10S 514/912 (2013.01);
Abstract
A method of treating or preventing age-related retinal dysfunction involves administering to a patient a pharmaceutically effective amount of a synthetic retinal derivative repeatedly over a duration of at least about 3 months. Effective synthetic retinal derivatives include 9-cis-retinyl esters, 11-cis-retinyl esters, derivatives and congeners thereof, and combinations thereof. Suitable ester substituents include carboxylates of C-Cmonocarboxylic acids and C-Cpolycarboxylic acids.