The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jan. 02, 2018

Filed:

Jul. 17, 2015
Applicant:

Allergan, Inc., Irvine, CA (US);

Inventors:

Ke Wu, Irvine, CA (US);

Shaoxin Feng, Tustin, CA (US);

Thomas K. Karami, Aliso Viejo, CA (US);

Scott W. Smith, Mission Viejo, CA (US);

Assignee:

ALLERGAN, INC., Irvine, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/192 (2006.01); C07C 59/54 (2006.01); A61K 9/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/192 (2013.01); A61K 9/0051 (2013.01); C07C 59/54 (2013.01); C07B 2200/13 (2013.01);
Abstract

The invention provides new crystalline forms of 7-[3,5-Dihydroxy-2-(3-hydroxy-5-phenyl-pent-1-enyl)-cyclopentyl]-hept-5-enoic acid. This compound is commonly referred to as 'bimatoprost acid.' The novel crystalline forms are designated forms I, II, and III. The invention crystalline forms are useful for solid ocular implant formulations, utilized in the treatment of various ocular conditions, such as, for example, ocular hypertension. In addition, invention crystalline forms are useful for solid or semisolid dosage formulations used to treat ocular hypertension.


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