The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 26, 2017

Filed:

Mar. 02, 2016
Applicants:

Mohammad Abdolahad, Tehran, IR;

Milad Gharooni, Tehran, IR;

Shamsoddin Mohajerzadeh, Tehran, IR;

Hamed Abiri, Tehran, IR;

Mohsen Janmaleki, Tehran, IR;

Inventors:

Mohammad Abdolahad, Tehran, IR;

Milad Gharooni, Tehran, IR;

Shamsoddin Mohajerzadeh, Tehran, IR;

Hamed Abiri, Tehran, IR;

Mohsen Janmaleki, Tehran, IR;

Assignee:

Other;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/02 (2006.01); G01N 33/483 (2006.01); H01L 21/02 (2006.01); G01N 27/02 (2006.01); G01N 33/50 (2006.01); G01N 33/574 (2006.01); G01N 27/327 (2006.01);
U.S. Cl.
CPC ...
G01N 33/4836 (2013.01); G01N 27/02 (2013.01); G01N 27/021 (2013.01); G01N 27/3278 (2013.01); G01N 33/5011 (2013.01); G01N 33/5044 (2013.01); G01N 33/574 (2013.01); H01L 21/02381 (2013.01); H01L 21/02488 (2013.01); H01L 21/02532 (2013.01); H01L 21/02603 (2013.01); H01L 21/02645 (2013.01); H01L 21/02653 (2013.01);
Abstract

A method for detection and monitoring a therapeutic effect of a cancer treatment drug is disclosed. The method includes steps of removing a malignant biological cell lines from a tumor; culturing the removed biological cell lines in a controlled set of conditions; seeding the cultured biological cell lines on silicon nanowire electrode arrays of an electrical cell-substrate impedance sensor (ECIS); adding a cancer treatment drug to the seeded biological cell lines to treat the seeded biological cell lines; and measuring an electrical impedance of the treated biological cell lines for detection and monitoring a therapeutic effect of the cancer treatment drug.


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