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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 9850504 B1

PDFFull Text
Date of Patent:
Dec. 26, 2017

Filed:

Jul. 02, 2014

Method for the enzymatic production of 3-buten-2-one

Applicants:

Scientist of Fortune S.a., Luxembourg, LU;

Global Bioenergies, Evry, FR;

Inventors:

Philippe Marliere, Tournai, BE;

Maria Anissimova, Nozay, FR;

Mathieu Allard, Saint-Vrain, FR;

Assignees:

Scientist of Fortune, S.A., Luxembourg, LU;

Global Bioenergies, Evry, FR;

Attorneys:

Michele M. Wales

InHouse Patent Counsel, LLC

Primary Examiner:

Scott Long

Assistant Examiner:

Paul Martin

Int. Cl.
CPC ...
C12N 9/88 (2006.01); C12P 7/16 (2006.01); C12N 1/00 (2006.01); C12P 5/02 (2006.01); C12P 7/26 (2006.01); C12N 9/04 (2006.01); C12N 9/02 (2006.01); C12N 15/52 (2006.01); C12P 7/04 (2006.01); C12N 15/70 (2006.01); C12P 19/32 (2006.01);
U.S. Cl.
CPC ...
C12P 7/16 (2013.01); C12N 1/00 (2013.01); C12N 9/001 (2013.01); C12N 9/0006 (2013.01); C12N 9/0008 (2013.01); C12N 9/88 (2013.01); C12N 15/52 (2013.01); C12N 15/70 (2013.01); C12P 5/026 (2013.01); C12P 7/04 (2013.01); C12P 7/26 (2013.01); C12P 19/32 (2013.01); C12Y 101/0103 (2013.01); C12Y 101/01034 (2013.01); C12Y 101/01184 (2013.01); C12Y 102/0105 (2013.01); C12Y 103/08001 (2013.01); C12Y 402/01017 (2013.01); C12Y 402/01018 (2013.01); C12Y 402/01055 (2013.01); C12Y 402/01059 (2013.01); C12Y 402/01074 (2013.01); C12Y 402/01116 (2013.01); C12Y 402/01127 (2013.01); Y02E 50/10 (2013.01);
Abstract

Described is a method for the production of 3-buten-2-one comprising the enzymatic conversion of 4-hydroxy-2-butanone into 3-buten-2-one by making use of an enzyme catalyzing 4-hydroxy-2-butanone dehydration, wherein said enzyme catalyzing 4-hydroxy-2-butanone dehydration is (a) a 3-hydroxypropiony-CoA dehydratase (EC 4.2.1.116), (b) a 3-hydroxybutyryl-CoA dehydratase (EC 4.2.1.55), (c) an enoyl-CoA hydratase (EC 4.2.1.17), (d) a 3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.59), (e) a crotonyl-[acyl-carrier-protein] hydratase (EC 4.2.1.58), (f) a 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.60), (g) a 3-hydroxypalmitoyl-[acyl-carrier-protein] dehydratase (EC 4.2.1.61), (h) a long-chain-enoyl-CoA hydratase (EC 4.2.1.74), or (i) a 3-methylglutaconyl-CoA hydratase (EC 4.2.1.18). The produced 3-buten-2-one can be further converted into 3-buten-2-ol and finally into 1,3-butadiene.

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