The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 26, 2017
Filed:
May. 30, 2006
Chae-ok Yun, Seoul, KR;
Joo-hang Kim, Seoul, KR;
Jin Soo Kim, Seoul, KR;
Hyun Chul Shin, Daejeon, KR;
Yoon a Kang, Seoul, KR;
Chae-Ok Yun, Seoul, KR;
Joo-Hang Kim, Seoul, KR;
Jin Soo Kim, Seoul, KR;
Hyun Chul Shin, Daejeon, KR;
Yoon A Kang, Seoul, KR;
Other;
Abstract
The present invention relates to a recombinant adenovirus capable of regulating angiogenesis, which comprises (a) an adenoviral UR (inverted terminal repeat) nucleotide sequence; and (b) a transcription regulatory sequence for a VEGF-A (vascular endothelial growth factor-A) gene comprising (i) a nucleotide sequence encoding a DNA binding domain comprising a zinc finger domain to bind to a site in a VEGF-A promoter sequence as set forth in nucleotides 1-2362 of SEQ ID NO:1, and (ii) a transcription activation domain or a transcription inhibitory domain linked to the nucleotide sequence encoding the DNA binding domain; and a pharmaceutical composition comprising the recombinant adenovirus.