The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 26, 2017
Filed:
Jul. 01, 2015
Salk Institute for Biological Studies, La Jolla, CA (US);
Sanofi, Paris, FR;
Tony Hunter, La Jolla, CA (US);
Stephen Rush Fuhs, La Jolla, CA (US);
Jill Meisenhelder, La Jolla, CA (US);
Jacques Mauger, Tucson, AZ (US);
Magda Stankova, Tucson, AZ (US);
Fahad Al-Obeidi, Tucson, AZ (US);
Robert A. Binne, Tucson, AZ (US);
Salk Institute for Biological Studies, La Jolla, CA (US);
Sanofi, Paris, FR;
Abstract
Isolated monoclonal antibodies and or antigen binding fragments thereof are disclosed herein that specifically bind polypeptides comprising a histidine phosphorylated at N3 (3-pHis). Nucleic acids encoding these antibodies, vectors including these nucleic acids, and host cells transformed with these vectors and nucleic acids are also disclosed. Methods are also disclosed for using these antibodies, such as for detection of polypeptides comprising a histidine phosphorylated at N3 (3-pHis). In some embodiments, the methods can be used to investigate signal transduction pathways.
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